Succinylcholine Chloride Injection and Vancomycin Hydrochloride
Determining the interaction of Succinylcholine Chloride Injection and Vancomycin Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using succinylcholine together with vancomycin can prolong the effects of succinylcholine. You should be closely monitored for prolong breathing cessation and respiratory paralysis after use of vancomycin. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Like other polypeptide antibiotics, vancomycin may prolong apnea and respiratory paralysis after use of neuromuscular blocking agents. The mechanism may be related to decreased intracellular potassium or decreased ionized serum calcium.
MANAGEMENT: Patients should be monitored for excessive and prolonged neuromuscular blockade.
- Kronenfeld MA, Thomas SJ, Turndorf H "Recurrence of neuromuscular blockade after reversal of vecuronium in a patient receiving polymyxin/amikacin sternal irrigation." Anesthesiology 65 (1986): 93-4
- Huang KC, Heise A, Shrader AK, Tsueda K "Vancomycin enhances the neuromuscular blockade of vecuronium." Anesth Analg 71 (1990): 194-6
Generic Name: succinylcholine
Brand name: Anectine, Quelicin
Synonyms: Succinylcholine
Generic Name: vancomycin
Brand name: FIRST-Vancomycin, Vancocin HCl Pulvules, First-Vancomycin 25, First-Vancomycin 50, Firvanq, Vancocin, First-Vancomycin 25, First-Vancomycin 50
Synonyms: Vancomycin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Succinylcholine Chloride Injection-Vancomycin injection
- Succinylcholine Chloride Injection-Vancomycin Intravenous, Injection
- Succinylcholine Chloride Injection-Vancomycin Oral Solution
- Succinylcholine Chloride Injection-Vandazole
- Succinylcholine Chloride Injection-Vandetanib
- Succinylcholine Chloride Injection-Vanos
- Vancomycin Hydrochloride-Suclear
- Vancomycin Hydrochloride-Sucralfate
- Vancomycin Hydrochloride-Sucralfate Oral Suspension
- Vancomycin Hydrochloride-Sucralfate Suspension
- Vancomycin Hydrochloride-Sucralfate Tablet
- Vancomycin Hydrochloride-Sucralfate Tablets