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Sucralfate Tablet and Zipsor

Determining the interaction of Sucralfate Tablet and Zipsor and the possibility of their joint administration.

Check result:

Sucralfate Tablet <> Zipsor

Relevance: 25.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Sucralfate may delay or decrease the pharmacologic effects of oral diclofenac. The mechanism may be related to reduced absorption. Data have conflicting and some studies suggest that sucralfate may have a protective effect on the gastric mucosa when taken with NSAIDs. Patients may be advised to take diclofenac 2 hours before or 6 hours after sucralfate if the interaction is to be avoided.

References

Pedrazzoli Junior J, Pierossi M de A, Muscara MN, Dias HF, da Silva CM, Mendes FD, de Nucci G "Short-term sucralfate administration alters potassium diclofenac absorption in healthy male volunteers." Br J Clin Pharmacol 43 (1997): 104-8

Sucralfate Tablet

Generic Name: sucralfate

Brand name: Carafate

Synonyms: Sucralfate

What is Sucralfate Tablet?

Zipsor

Generic Name: diclofenac

Brand name: Zipsor, Cambia, Cataflam, Zorvolex, Voltaren, Voltaren-XR, Dyloject, also Cambia

Synonyms: n.a.

What is Zipsor?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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