Sudafed PE Cold & Cough and Wakix Tablets
Determining the interaction of Sudafed PE Cold & Cough and Wakix Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.MONITOR: Coadministration with pitolisant may reduce plasma concentrations of substrates of CYP450 2C, P-glycoprotein (P-gp), and uridine diphosphate glucuronosyltransferases (UGTs). Based on in vitro data, pitolisant and its main metabolites may induce CYP450 2C, P-gp, and UGTs. Clinical data are not available. MANAGEMENT: Caution is recommended if pitolisant is used in combination with substrates of CYP450 2C, P-gp, and/or UGTs. Clinical and laboratory monitoring may be appropriate for some drugs whenever pitolisant is added to or withdrawn from therapy. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Professional:MONITOR: Coadministration with pitolisant may reduce plasma concentrations of substrates of CYP450 2C, P-glycoprotein (P-gp), and uridine diphosphate glucuronosyltransferases (UGTs). Based on in vitro data, pitolisant and its main metabolites may induce CYP450 2C, P-gp, and UGTs. Clinical data are not available.
MANAGEMENT: Caution is recommended if pitolisant is used in combination with substrates of CYP450 2C, P-gp, and/or UGTs. Clinical and laboratory monitoring may be appropriate for some drugs whenever pitolisant is added to or withdrawn from therapy.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Generic Name: acetaminophen / dextromethorphan / guaifenesin / phenylephrine
Brand name: DayQuil Severe Cold & Flu, Delsym Cough Plus Cold Day Time, Mucinex Children's Cold, Cough & Sore Throat, Mucinex Fast-Max Severe Cold, Sudafed PE Cold & Cough, Tylenol Cold & Flu Severe, Tylenol Cold Multi-Symptom Severe, Mucinex Sinus-Max, Sudafed PE Cold/Cough, Tylenol Cold Head Congestion, Tylenol Cold Multi Symptom, Tylenol Cold/Flu Severe, Vicks DayQuil Severe Cold/Flu
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Sudafed PE Cold & Cough-Wal-Fex
- Sudafed PE Cold & Cough-Wal-finate
- Sudafed PE Cold & Cough-Wal-itin
- Sudafed PE Cold & Cough-Wal-Zyr D
- Sudafed PE Cold & Cough-Walgreens Ibuprofen Junior Strength
- Sudafed PE Cold & Cough-Warfarin
- Wakix Tablets-Sudafed PE Cold & Cough Child
- Wakix Tablets-Sudafed PE Head Congestion
- Wakix Tablets-Sudafed PE Non-Drying Sinus
- Wakix Tablets-Sudafed PE Pressure + Pain
- Wakix Tablets-Sudafed PE Pressure+Pain+Cold
- Wakix Tablets-Sudafed PE Pressure+Pain+Cough
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets 
Sudafed PE Cold & Cough - Wakix Tablets