Sugammadex Sodium and Twinrix Preservative-Free

• Generic Name: sugammadex
• Dosage Forms: n.a.
• Other Brand Names: Bridion

Used to reverse neuromuscular blockade induced by rocuronium or vecuronium in patients undergoing surgery.

Reduces time to recovery of neuromuscular function when administered at moderate (reappearance of the second twitch [T2] in a train-of-four [TOF] stimulation) or deep (1–2 posttetanic counts [PTC] and no twitch responses to TOF stimulation) neuromuscular blockade compared with neostigmine.

Highest recommended dose of 16 mg/kg may be used for immediate reversal of profound neuromuscular blockade induced by high-dose (1.2 mg/kg) rocuronium bromide if clinically indicated; when given shortly (approximately 3 minutes) after the onset of blockade, reduces time to recovery of neuromuscular function compared with spontaneous recovery from succinylcholine.

Effective reversal agent for steroidal neuromuscular blocking agents rocuronium and vecuronium only; do not use for reversal of nonsteroidal neuromuscular blocking agents (e.g., succinylcholine, benzylisoquinolinium compounds [atracurium, mivacurium]).

Not studied in the intensive care unit (ICU) setting.

• Generic Name: hepatitis a adult vaccine / hepatitis b adult vaccine
• Dosage Forms: injection, suspension
• Other Brand Names: Twinrix Preservative-Free, Twinrix

Hepatitis A and B are serious diseases caused by virus.

Hepatitis A is spread through contact with the stool (bowel movements) of a person infected with the hepatitis A virus. This usually occurs by eating food or drinking water that has become contaminated as a result of handling by an infected person.

Hepatitis B is spread through blood or bodily fluids, sexual contact or sharing IV drug needles with an infected person, or during childbirth when a baby is born to a mother who is infected.

Hepatitis causes inflammation of the liver, vomiting, and jaundice (yellowing of the skin or eyes). Hepatitis can lead to liver cancer, cirrhosis, or death.

The hepatitis A and B vaccine is used to help prevent these diseases in adults. The vaccine works by exposing you to a small dose of the virus, which causes the body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body.

This vaccine is recommended for adults with risk factors for getting hepatitis A or B, including:

• having chronic liver problems, such as cirrhosis or hepatitis C, or needing a liver transplant;

• using intravenous (IV) drugs;

• living with a person who has either hepatitis A or B infection;

• having sexual contact with an infected person;

• having more than one sex partner in 6 months;

• being male and having sex with other men;

• having a blood clotting disorder such as hemophilia;

• being on dialysis or receiving blood transfusions;

• living in a correctional institution;

• being in the military or traveling to high-risk areas; and

• working in healthcare or public safety and being exposed to infected blood or body fluids.

Like any vaccine, the hepatitis A and B vaccine may not provide protection from disease in every person.