Sugammadex Sodium and Verapamil oral/injection

• Generic Name: sugammadex
• Dosage Forms: n.a.
• Other Brand Names: Bridion

Used to reverse neuromuscular blockade induced by rocuronium or vecuronium in patients undergoing surgery.

Reduces time to recovery of neuromuscular function when administered at moderate (reappearance of the second twitch [T2] in a train-of-four [TOF] stimulation) or deep (1–2 posttetanic counts [PTC] and no twitch responses to TOF stimulation) neuromuscular blockade compared with neostigmine.

Highest recommended dose of 16 mg/kg may be used for immediate reversal of profound neuromuscular blockade induced by high-dose (1.2 mg/kg) rocuronium bromide if clinically indicated; when given shortly (approximately 3 minutes) after the onset of blockade, reduces time to recovery of neuromuscular function compared with spontaneous recovery from succinylcholine.

Effective reversal agent for steroidal neuromuscular blocking agents rocuronium and vecuronium only; do not use for reversal of nonsteroidal neuromuscular blocking agents (e.g., succinylcholine, benzylisoquinolinium compounds [atracurium, mivacurium]).

Not studied in the intensive care unit (ICU) setting.

• Generic Name: verapamil
• Dosage Forms: n.a.
• Other Brand Names: Calan, Isoptin SR, Verelan, Isoptin, Calan SR, Isoptin IV, Covera-HS, Verelan PM

Verapamil is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders.

Verapamil injection is used to rapidly or temporarily restore normal heartbeats in people with certain heart rhythm disorders.

Verapamil may also be used for purposes not listed in this medication guide.