Sugammadex Sodium and Zegerid (Omeprazole and Sodium Bicarbonate Capsules)

• Generic Name: sugammadex
• Dosage Forms: n.a.
• Other Brand Names: Bridion

Used to reverse neuromuscular blockade induced by rocuronium or vecuronium in patients undergoing surgery.

Reduces time to recovery of neuromuscular function when administered at moderate (reappearance of the second twitch [T2] in a train-of-four [TOF] stimulation) or deep (1–2 posttetanic counts [PTC] and no twitch responses to TOF stimulation) neuromuscular blockade compared with neostigmine.

Highest recommended dose of 16 mg/kg may be used for immediate reversal of profound neuromuscular blockade induced by high-dose (1.2 mg/kg) rocuronium bromide if clinically indicated; when given shortly (approximately 3 minutes) after the onset of blockade, reduces time to recovery of neuromuscular function compared with spontaneous recovery from succinylcholine.

Effective reversal agent for steroidal neuromuscular blocking agents rocuronium and vecuronium only; do not use for reversal of nonsteroidal neuromuscular blocking agents (e.g., succinylcholine, benzylisoquinolinium compounds [atracurium, mivacurium]).

Not studied in the intensive care unit (ICU) setting.

• Generic Name: omeprazole / sodium bicarbonate
• Dosage Forms: capsule; powder, for suspension
• Other Brand Names: Zegerid, Zegerid OTC

• It is used to treat gastroesophageal reflux disease (GERD; acid reflux).
• It is used to treat heartburn.
• It is used to treat GI (gastrointestinal) ulcers.
• It is used to treat or prevent ulcers of the swallowing tube (esophagus).
• It may be given to you for other reasons. Talk with the doctor.