Sulfinpyrazone and Verapamil oral/injection
Determining the interaction of Sulfinpyrazone and Verapamil oral/injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Sulfinpyrazone may increase the clearance of verapamil. Serum verapamil levels and verapamil effects may be decreased. The mechanism and clinical significance are unknown. The effectiveness of verapamil during therapy should be monitored. Also, the clinician should be aware that verapamil effectiveness and risk of toxicity may increase when sulfinpyrazone is discontinued.
- Wing LM, Miners JO, Lillywhite KJ "Verapamil disposition: effects of sulphinpyrazone and cimetidine." Br J Clin Pharmacol 19 (1985): 385-91
Generic Name: sulfinpyrazone
Brand name:
Synonyms: Sulfinpyrazone (Oral)
Generic Name: verapamil
Brand name: Calan, Isoptin SR, Verelan, Isoptin, Calan SR, Isoptin IV, Covera-HS, Verelan PM
Synonyms: Verapamil
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Sulfinpyrazone-Verapamil Sustained-Release Capsules
- Sulfinpyrazone-Verdeso
- Sulfinpyrazone-Verdrocet
- Sulfinpyrazone-Verelan
- Sulfinpyrazone-Verelan PM
- Sulfinpyrazone-Veripred 20
- Verapamil oral/injection-Sulfisoxazole
- Verapamil oral/injection-Sulfo-Lo Topical
- Verapamil oral/injection-Sulfoam
- Verapamil oral/injection-Sulfoam Topical
- Verapamil oral/injection-Sulfur and Salicylic Acid Lotion
- Verapamil oral/injection-Sulfur and Salicylic Acid Shampoo