Sunosi and Zelapar
Determining the interaction of Sunosi and Zelapar and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.CONTRAINDICATED: Coadministration of solriamfetol with other drugs that also inhibit the reuptake of dopamine or norepinephrine, including monoamine oxidase inhibitors (MAOIs), may increase the risk of hypertensive reactions including death, stroke, myocardial infarction, aortic dissection, pulmonary edema, and renal failure. Additionally, MAOIs can increase dopaminergic and noradrenergic activity by inhibiting the metabolism of dopamine and norepinephrine. MANAGEMENT: Concomitant use of solriamfetol with MAOIs is considered contraindicated. At least 14 days should elapse between discontinuation of MAOI therapy and initiation of treatment with solriamfetol. References "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals, Palo Alto, CA.
Professional:CONTRAINDICATED: Coadministration of solriamfetol with other drugs that also inhibit the reuptake of dopamine or norepinephrine, including monoamine oxidase inhibitors (MAOIs), may increase the risk of hypertensive reactions including death, stroke, myocardial infarction, aortic dissection, pulmonary edema, and renal failure. Additionally, MAOIs can increase dopaminergic and noradrenergic activity by inhibiting the metabolism of dopamine and norepinephrine.
MANAGEMENT: Concomitant use of solriamfetol with MAOIs is considered contraindicated. At least 14 days should elapse between discontinuation of MAOI therapy and initiation of treatment with solriamfetol.
- "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals, Palo Alto, CA.
Generic Name: selegiline
Brand name: Eldepryl, Zelapar, Emsam
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.