Sustiva and Viekira XR

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using efavirenz together with dasabuvir is not recommended. These medications given in combination have been poorly tolerated and led to liver problems in some cases. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

CONTRAINDICATED: Coadministration of efavirenz-based antiretroviral regimens with ombitasvir/paritaprevir/ritonavir plus dasabuvir has been reported to be poorly tolerated and resulted in liver enzyme elevations.

MANAGEMENT: Concomitant use of efavirenz with ombitasvir/paritaprevir/ritonavir plus dasabuvir is considered contraindicated.

Sustiva

Generic Name: efavirenz

Brand name: Sustiva

Synonyms: n.a.

What is Sustiva?

Viekira XR

Generic Name: dasabuvir / ombitasvir / paritaprevir / ritonavir

Brand name: Viekira Pak, Viekira XR

Synonyms: n.a.

What is Viekira XR?