Sx1 Medicated Post-Operative System and Tobramycin inhalation
Determining the interaction of Sx1 Medicated Post-Operative System and Tobramycin inhalation and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Both neomycin topical and tobramycin belong to the same class of antibiotics known as aminoglycosides. Since the medication in neomycin topical may be absorbed from the skin, combining it with tobramycin may increase the risk of serious side effects reported with aminoglycosides such as hearing loss, respiratory depression, and kidney problems. Patients who may be particularly susceptible include the elderly and those who are dehydrated or have preexisting kidney disease. Neomycin topical should generally not be used with tobramycin in circumstances where significant absorption could occur (for example: application to burnt or broken skin; use of large quantities or on large areas for prolonged periods). Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Let your doctor know immediately if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, or signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Topically applied aminoglycosides may be systemically absorbed and have potentially additive effects with systemically administered aminoglycosides. The risk of oto- and nephrotoxicity and other adverse effects of aminoglycosides may be increased.
MANAGEMENT: Topical preparations containing an aminoglycoside should not be used with other aminoglycosides in circumstances where significant systemic absorption could occur (e.g., application to burnt or broken skin; use of large quantities or on large areas for prolonged periods). The normally recommended dosages of these products should not be exceeded.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: bacitracin / lidocaine / neomycin / polymyxin b topical
Brand name:
Synonyms: n.a.
Generic Name: tobramycin
Brand name: Bethkis, Kitabis Pak, Tobi, TOBI Podhaler
Synonyms: Tobramycin (inhalation), Tobramycin (Oral Inhalation)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Sx1 Medicated Post-Operative System-Tobramycin Inhalation Powder
- Sx1 Medicated Post-Operative System-Tobramycin Inhalation Solution
- Sx1 Medicated Post-Operative System-Tobramycin injection
- Sx1 Medicated Post-Operative System-Tobramycin Sulfate
- Sx1 Medicated Post-Operative System-Tobramycin Sulfate ADD-Vantage injection
- Sx1 Medicated Post-Operative System-Tocainide
- Tobramycin inhalation-Syeda
- Tobramycin inhalation-Sylatron
- Tobramycin inhalation-Sylvant
- Tobramycin inhalation-Symax Duotab
- Tobramycin inhalation-Symax FasTab
- Tobramycin inhalation-Symax FasTabs