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Symproic and Vivitrol

Determining the interaction of Symproic and Vivitrol and the possibility of their joint administration.

Check result:
Symproic <> Vivitrol
Relevance: 21.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using naltrexone together with naldemedine may increase the risk of withdrawal. Symptoms may include sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Coadministration of naloxegol or naldemedine with other opioid antagonists may result in additive pharmacologic effects and increased risk of opioid withdrawal.

MANAGEMENT: Concomitant use of naloxegol or naldemedine with other opioid antagonists should generally be avoided.

References
  • "Product Information. Movantik (naloxegol)." Astra-Zeneca Pharmaceuticals, Wilmington, DE.
Symproic

Generic Name: naldemedine

Brand name: Symproic

Synonyms: n.a.

Vivitrol

Generic Name: naltrexone

Brand name: Vivitrol, Depade, ReVia

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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