Tandem Capsules and Zinc Gluconate Capsules and Tablets
Determining the interaction of Tandem Capsules and Zinc Gluconate Capsules and Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Iron and zinc may reduce each other's absorption when they are coadministered orally. The mechanism of interaction is unknown. In clinical studies, concurrent supplementation with iron and zinc was associated with reduced efficacy in improving the growth and iron and zinc status of malnourished infants compared to supplementation with either one alone. It is not known whether the interaction occurs in adults. In any case, the clinical significance is probably minimal in healthy individuals. However, monitoring for reduced therapeutic response may be advisable in malnourished patients. Limited data suggest that the magnitude of the interaction may be lessened by separating the times of administration of each by 12 hours.
- Lind T, Lonnerdal B, Stenlund H, et al. "A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: interactions between iron and zinc." Am J Clin Nutr 77 (2003): 883-90
- Sreedhar B "Conflicting evidence of iron and zinc interactions in humans: does iron affect zinc absorption?" Am J Clin Nutr 78 (2003): 1226; author reply 1226-7
Generic Name: ferrous fumarate / iron polysaccharide
Brand name: Tandem
Synonyms: Ferrous Fumarate and Polysaccharide Iron Complex
Generic Name: zinc gluconate
Brand name: Orazinc, Orazinc 110
Synonyms: Zinc gluconate, Zinc Gluconate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Tandem Capsules-Zinc Gluconate Extended-Release Tablets
- Tandem Capsules-Zinc Gluconate Lozenges
- Tandem Capsules-Zinc sulfate
- Tandem Capsules-Zinc Sulfate Capsules and Tablets
- Tandem Capsules-Zinc Sulfate Extended-Release Tablets
- Tandem Capsules-Zinc Sulfate Injection
- Zinc Gluconate Capsules and Tablets-Tandem DHA
- Zinc Gluconate Capsules and Tablets-Tandem OB
- Zinc Gluconate Capsules and Tablets-Tandem Plus
- Zinc Gluconate Capsules and Tablets-Tannic-12 S
- Zinc Gluconate Capsules and Tablets-Tanzeum
- Zinc Gluconate Capsules and Tablets-Tapazole