Targin and Toujeo SoloStar

• Generic Name: naloxone / oxycodone
• Dosage Forms: n.a.
• Other Brand Names: Targiniq ER

Oxycodone and naloxone combination is used to treat pain severe enough to require daily, around-the-clock, long-term opioid treatment and when other pain medicines did not work well enough or cannot be tolerated.

Oxycodone belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain. Naloxone is used to treat an opioid emergency such as an overdose or a possible overdose of a narcotic medicine.

Oxycodone and naloxone combination should not be used if you need pain medicine for just a short time, such as when recovering from surgery. Do not use this medicine to relieve mild pain, or in situations when non-narcotic medication is effective. This medicine should not be used to treat pain that you only have once in a while or "as needed".

When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.

• Generic Name: insulin glargine
• Dosage Forms: injection, solution
• Other Brand Names: Toujeo SoloStar, Toujeo Max SoloStar, Basaglar KwikPen, Lantus, Lantus Solostar Pen, Lantus OptiClik Cartridge, Lantus SoloStar

Toujeo SoloStar is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours.

Toujeo SoloStar is used to improve blood sugar control in adults and children with diabetes mellitus. This medicine is used to treat type 1 or type 2 diabetes in adults, and type 1 diabetes children who are at least 6 years old.

Some brands of Toujeo SoloStar are for use only in adults. Carefully follow all instructions for the brand of insulin glargine you are using.

Toujeo SoloStar may also be used for purposes not listed in this medication guide.