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Technetium tc 99m tilmanocept Injection and Zorcaine

Determining the interaction of Technetium tc 99m tilmanocept Injection and Zorcaine and the possibility of their joint administration.

Check result:

Technetium tc 99m tilmanocept Injection <> Zorcaine

Relevance: 21.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Tilmanocept should not be mixed or coadministered with articaine or other local anesthetics due to potential impairment of lymph nodal mapping.

Professional:

GENERALLY AVOID: Locally injected anesthetics have been reported to reduce lymphatic flow of Technetium Tc 99m tilmanocept in animal studies.

MANAGEMENT: Co-injection (mixture) of local anesthetics with Technetium Tc 99m tilmanocept is not recommended due to potential impairment of lymph nodal mapping.

References

"Product Information. Lymphoseek (tilmanocept)." Navidea Biopharmaceuticals, Dublin, OH.

Technetium tc 99m tilmanocept Injection

Generic Name: tilmanocept

Brand name:

Synonyms: Technetium tc 99m tilmanocept (Injection)

What is Technetium tc 99m tilmanocept Injection?

Zorcaine

Generic Name: articaine / epinephrine

Brand name: Articadent, Orabloc, Septocaine with Epinephrine 1: 100, 000, Septocaine with Epinephrine 1: 200, Zorcaine, Septocaine

Synonyms: n.a.

What is Zorcaine?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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