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Tegaserod and Zovia 1/50

Determining the interaction of Tegaserod and Zovia 1/50 and the possibility of their joint administration.

Check result:

Tegaserod <> Zovia 1/50

Relevance: 08.04.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Tegaserod decreased levonorgestrel plasma concentrations by less than 10% in a clinical study with a low-dose triphasic oral contraceptive (n=45). The mechanism is unknown. There were no changes in ethinyl estradiol concentrations or in contraceptive efficacy. No action is necessary.

References

Vickers AE, Zollinger M, Dannecker R, Tynes R, Heitz F, Fischer V "In vitro metabolism of tegaserod in human liver and intestine: assessment of drug interactions." Drug Metab Dispos 29 (2001): 1269-76
"Product Information. Zelnorm (tegaserod)." Novartis Pharmaceuticals, East Hanover, NJ.

Tegaserod

Generic Name: tegaserod

Brand name: Zelnorm

Synonyms: Tegaserod Maleate

What is Tegaserod?

Zovia 1/50

Generic Name: ethinyl estradiol / ethynodiol

Brand name: Kelnor, Zovia 1/35, Zovia 1/50, Demulen 1/35, Demulen 1/50, Zovia 1/35e, Kelnor 1/50, Kelnor 1/35, Zovia 1/50e

Synonyms: Zovia 1/50E

What is Zovia 1/50?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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