About us Contacts Drug interactions: 390 212
Drug search by name

Tegretol and Zarontin (Ethosuximide Solution)

Determining the interaction of Tegretol and Zarontin (Ethosuximide Solution) and the possibility of their joint administration.

Check result:
Tegretol <> Zarontin (Ethosuximide Solution)
Relevance: 23.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Carbamazepine may decrease serum levels of ethosuximide. The mechanism is related to carbamazepine induction of ethosuximide metabolism. The clinical significance of this potential interaction is unknown.

References
  • Giaccone M, Bartoli A, Gatti G, Marchiselli R, Pisani F, Latella MA, Perucca E "Effect of enzyme inducing anticonvulsants on ethosuximide pharmacokinetics in epileptic patients." Br J Clin Pharmacol 41 (1996): 575-9
  • Warren JW Jr, Benmaman JD, Wannamaker BB, Levy RH "Kinetics of a carbamazepine-ethosuximide interaction." Clin Pharmacol Ther 28 (1980): 646-51
Tegretol

Generic Name: carbamazepine

Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: n.a.

Zarontin (Ethosuximide Solution)

Generic Name: ethosuximide

Brand name: Zarontin

Synonyms: Zarontin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle