Telotristat Etiprate and Timothy grass pollen allergen extract Sublingual

• Generic Name: telotristat
• Dosage Forms: n.a.
• Other Brand Names: Xermelo

Used (in combination with somatostatin analog therapy) for treatment of carcinoid syndrome diarrhea inadequately controlled by somatostatin analog therapy alone (designated an orphan drug by FDA for the treatment of carcinoid syndrome in patients with neuroendocrine tumors).

Carcinoid syndrome, a condition associated with serotonin overproduction, is characterized by flushing, diarrhea, wheezing, occasionally congestive heart failure, and various other manifestations. Although somatostatin analogs (e.g., octreotide, lanreotide) are standard treatment for carcinoid syndrome and are effective initially in most patients, some patients may not respond adequately or may develop recurrent symptoms, including diarrhea, despite therapy.

In clinical studies, telotristat ethyl reduced the frequency of daily bowel movements in patients with carcinoid syndrome diarrhea. Reductions in other symptoms of carcinoid syndrome (e.g., abdominal pain, flushing) not observed.

• Generic Name: timothy grass pollen allergen extract
• Dosage Forms: n.a.
• Other Brand Names: Grastek

Grastek® is an allergen extract which is used as an immunotherapy to treat symptoms of grass pollen allergic rhinitis with or without conjunctivitis. This is confirmed by a positive skin test that is caused by timothy grass pollen allergen extract.

Timothy grass pollen allergen extract is available only with your doctor's prescription.