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TheoCap and Zyrtec

Determining the interaction of TheoCap and Zyrtec and the possibility of their joint administration.

Check result:

TheoCap <> Zyrtec

Relevance: 23.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with theophylline may decrease the clearance of cetirizine. The mechanism of interaction is unknown. According to the product labeling, a small decrease in the clearance of cetirizine was observed when given with a 400 mg dose of theophylline, and it is possible that larger theophylline doses could have a greater effect. No clinically significant drug interaction has been found with theophylline at a low dose. Steady-state cetirizine (10 mg twice daily for 3.5 days) has also been found to have no significant effects on the pharmacokinetics of theophylline (240 mg intravenously one hour after the last dose of cetirizine) in six healthy volunteers compared to placebo, and vice versa.

References

"Product Information. Zyrtec (cetirizine)." Pfizer US Pharmaceuticals, New York, NY.

TheoCap

Generic Name: theophylline

Brand name: Elixophyllin, Theo-24, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCap

Synonyms: TheoCap (Oral)

What is TheoCap?

Zyrtec

Generic Name: cetirizine

Brand name: All Day Allergy, All Day Allergy Children's, GoodSense All Day Allergy, Indoor/Outdoor Allergy Relief, Zyrtec, Zyrtec

Synonyms: n.a.

What is Zyrtec?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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