Theophylline Liquid and Zyrtec (Cetirizine Syrup)
Determining the interaction of Theophylline Liquid and Zyrtec (Cetirizine Syrup) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with theophylline may decrease the clearance of cetirizine. The mechanism of interaction is unknown. According to the product labeling, a small decrease in the clearance of cetirizine was observed when given with a 400 mg dose of theophylline, and it is possible that larger theophylline doses could have a greater effect. No clinically significant drug interaction has been found with theophylline at a low dose. Steady-state cetirizine (10 mg twice daily for 3.5 days) has also been found to have no significant effects on the pharmacokinetics of theophylline (240 mg intravenously one hour after the last dose of cetirizine) in six healthy volunteers compared to placebo, and vice versa.
- "Product Information. Zyrtec (cetirizine)." Pfizer US Pharmaceuticals, New York, NY.
Generic Name: theophylline
Brand name: Elixophyllin, Theo-24, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCap
Synonyms: Theophylline
Generic Name: cetirizine
Brand name: All Day Allergy, All Day Allergy Children's, GoodSense All Day Allergy, Indoor/Outdoor Allergy Relief, Zyrtec, Zyrtec
Synonyms: Zyrtec
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Theophylline Liquid-Zyrtec Capsule
- Theophylline Liquid-Zyrtec Syrup
- Theophylline Liquid-Zyrtec Tablets
- Theophylline Liquid-Zyrtec-D
- Theophylline Liquid-Zyrtec-D 12 Hour
- Theophylline Liquid-ZyrTEC-D Allergy & Congestion
- Zyrtec (Cetirizine Syrup)-Theophylline Oral Solution
- Zyrtec (Cetirizine Syrup)-Theophylline Sustained-Release Capsules
- Zyrtec (Cetirizine Syrup)-Theophylline Sustained-Release Tablets
- Zyrtec (Cetirizine Syrup)-Thera-D 2000
- Zyrtec (Cetirizine Syrup)-Thera-Gesic
- Zyrtec (Cetirizine Syrup)-Thera-Gesic Plus