Theraflu Severe Cold & Congestion Non-Drowsy and Wakix
Determining the interaction of Theraflu Severe Cold & Congestion Non-Drowsy and Wakix and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.MONITOR: Coadministration with pitolisant may reduce plasma concentrations of substrates of CYP450 2C, P-glycoprotein (P-gp), and uridine diphosphate glucuronosyltransferases (UGTs). Based on in vitro data, pitolisant and its main metabolites may induce CYP450 2C, P-gp, and UGTs. Clinical data are not available. MANAGEMENT: Caution is recommended if pitolisant is used in combination with substrates of CYP450 2C, P-gp, and/or UGTs. Clinical and laboratory monitoring may be appropriate for some drugs whenever pitolisant is added to or withdrawn from therapy. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Professional:MONITOR: Coadministration with pitolisant may reduce plasma concentrations of substrates of CYP450 2C, P-glycoprotein (P-gp), and uridine diphosphate glucuronosyltransferases (UGTs). Based on in vitro data, pitolisant and its main metabolites may induce CYP450 2C, P-gp, and UGTs. Clinical data are not available.
MANAGEMENT: Caution is recommended if pitolisant is used in combination with substrates of CYP450 2C, P-gp, and/or UGTs. Clinical and laboratory monitoring may be appropriate for some drugs whenever pitolisant is added to or withdrawn from therapy.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Generic Name: acetaminophen / dextromethorphan / pseudoephedrine
Brand name: Alka-Seltzer Plus Flu Liquigels, Comtrex Non-Drowsy, Dayquil Liquicaps, Daytime Cold, Non-Drowsy Daytime, Robitussin Honey Flu Non-Drowsy, Theraflu Daytime Severe Cold, Theraflu Severe Cold & Congestion Non-Drowsy, Triaminic Cough & Sore Throat, Triaminic Softchew Throat Pain and Cough, Triaminic Softchews Cough & Sore Throat, EQL Severe Cold, GNP Day Time D Cold/Flu, PX Daytime Multi-Symptom, RA Acetaminophen Flu Cold
Synonyms: Theraflu (pseudoephedrine) Daytime Severe Cold
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Theraflu Severe Cold & Congestion Non-Drowsy-Wakix Tablets
- Theraflu Severe Cold & Congestion Non-Drowsy-Wal-Fex
- Theraflu Severe Cold & Congestion Non-Drowsy-Wal-finate
- Theraflu Severe Cold & Congestion Non-Drowsy-Wal-itin
- Theraflu Severe Cold & Congestion Non-Drowsy-Wal-Zyr D
- Theraflu Severe Cold & Congestion Non-Drowsy-Walgreens Ibuprofen Junior Strength
- Wakix-Theraflu Severe Cold & Cough Nighttime
- Wakix-Theraflu Severe Cold and Cough
- Wakix-Theraflu Severe Cold Nighttime
- Wakix-Theraflu Sinus & Cold
- Wakix-Theraflu Warming Flu & Sore Throat
- Wakix-Theraflu Warming Relief Cold & Chest Congestion