About us Contacts Drug interactions: 390 212
Drug search by name

Tiglutik and Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)

Determining the interaction of Tiglutik and Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets) and the possibility of their joint administration.

Check result:
Tiglutik <> Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)
Relevance: 24.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Omeprazole may decrease the serum concentration of riluzole. Riluzole is metabolized by the CYP450 1A2 isoenzyme. Omeprazole may induce this particular isoenzyme, possibly increasing the riluzole elimination rate. The clinical significance of this interaction is not known. During coadministration, the patient should be more closely monitored for altered clinical effect.

References
  • "Product Information. Rilutek (riluzole)." Rhone-Poulenc Rorer, Collegeville, PA.
Tiglutik

Generic Name: riluzole

Brand name: Rilutek, Tiglutik

Synonyms: n.a.

Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)

Generic Name: omeprazole / sodium bicarbonate

Brand name: Zegerid, Zegerid OTC

Synonyms: Zegerid

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.