Tisagenlecleucel Intravenous and Ultane Novation

• Generic Name: tisagenlecleucel
• Dosage Forms: n.a.
• Other Brand Names: Kymriah

Tisagenlecleucel injection is used to treat B-cell acute lymphoblastic leukemia (ALL) that has come back a second or later time or after other medicines did not work well in patients up to 25 years of age. Leukemia is a type of cancer where the body makes abnormal white blood cells.

Tisagenlecleucel injection is also used to treat diffuse large B-cell lymphoma (DLBCL) that has come back a second or later time or after at least 2 other medicines did not work well. Lymphoma is a type of cancer where the body makes abnormal white blood cells.

Tisagenlecleucel injection is an antineoplastic (cancer) medicine that is made from your own white blood cells. These cells are reprogrammed to contain a chimeric antigen receptor (CAR) to identify the cancer cells from the normal cells and kill them. Before you begin treatment, talk to your doctor about the benefits of tisagenlecleucel as well as the possible risks of receiving it.

Tisagenlecleucel is available only under a restricted distribution program called Kymriah® REMS (Risk Evaluation and Mitigation Strategy) Program.

• Generic Name: sevoflurane
• Dosage Forms: inhalant
• Other Brand Names: Sojourn, Ultane

Sevoflurane belongs to the group of medicines known as general anesthetics. Sevoflurane is used to cause general anesthesia (loss of consciousness) before and during surgery. It is inhaled (breathed in). Although sevoflurane can be used by itself, combinations of anesthetics are often used together. This helps produce more effective anesthesia in some patients.

General anesthetics are given only by or under the immediate supervision of a doctor trained to use them. If you will be receiving a general anesthetic during your surgery, your anesthesiologist or nurse anesthetist will give you the medicine and closely follow your progress.