Tobi Podhaler inhalation and Tranylcypromine Sulfate

• Generic Name: tobramycin
• Dosage Forms: inhalation capsule
• Other Brand Names: Bethkis, Kitabis Pak, Tobi, TOBI Podhaler

Tobi Podhaler is an antibiotic that is inhaled into the lungs using a nebulizer. This medicine inhalation is used to treat lung infections in patients with cystic fibrosis.

Tobi Podhaler is for use in adults and children who are at least 6 years old.

Tobi Podhaler may also be used for purposes not listed in this medication guide.

• Generic Name: tranylcypromine
• Dosage Forms: n.a.
• Other Brand Names: Parnate

Treatment of major depressive disorder without melancholia.

Efficacy in major depressive disorder with melancholia (endogenous features) not established.

MAO inhibitors appear particularly effective in treatment of major depressive disorder with atypical features, although other antidepressants (e.g., SSRIs) may initially be used because of their more favorable adverse effect profile.

Because of potential for serious adverse effects and necessity of dietary restrictions, MAO inhibitors (e.g., phenelzine, tranylcypromine) generally are not used as initial therapy for major depressive disorder, but are reserved for carefully selected patients who can be closely supervised and who have depression refractory to other antidepressants (e.g., SSRIs, SNRIs, TCAs) or in whom other therapies are contraindicated.