Tofranil-PM and Ultane Novation
Determining the interaction of Tofranil-PM and Ultane Novation and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Before getting anesthesia with sevoflurane, tell your doctor if you are taking imipramine. Using these medications together may cause low blood pressure and irregular heart rhythm. In some cases, your doctor may want you to stop taking imipramine for 10 to 14 days before you undergo surgery. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: The concomitant use of general anesthetics with tricyclic antidepressants may increase the risk of hypotension and cardiac arrhythmias. The presence of pancuronium may increase the risk of tachyarrhythmias. Enflurane may also increase the risk of seizures when given to patients who have been taking tricyclic antidepressants.
MANAGEMENT: Close monitoring is recommended when these drugs are used together.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: imipramine
Brand name: Tofranil-PM, Tofranil
Synonyms: n.a.
Generic Name: sevoflurane
Brand name: Sojourn, Ultane
Synonyms: Sevoflurane
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Tofranil-PM-UltimateCare ONE NF
- Tofranil-PM-Ultiva
- Tofranil-PM-Ultra Enerforce
- Tofranil-PM-Ultra Freeda A-Free
- Tofranil-PM-Ultra Freeda Iron-Free
- Tofranil-PM-Ultra Freeda With Iron
- Ultane Novation-Tol-Tab
- Ultane Novation-Tolazamide
- Ultane Novation-Tolbutamide
- Ultane Novation-Tolcapone
- Ultane Novation-Tolectin 600
- Ultane Novation-Tolectin DS