Tolazamide and Zevalin

• Generic Name: tolazamide
• Dosage Forms: n.a.
• Other Brand Names: Tolinase

Tolazamide causes the pancreas to produce insulin and increases your body's response to it.

Tolazamide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Tolazamide is not for treating type 1 diabetes.

Tolazamide may also be used for purposes not listed in this medication guide.

• Generic Name: ibritumomab
• Dosage Forms: injection
• Other Brand Names: Y-90 Zevalin, In-111 Zevalin

Part of a specific therapeutic regimen (ibritumomab tiuxetan therapeutic regimen) for treatment of relapsed or refractory low-grade or follicular B-cell non-Hodgkin’s lymphoma (NHL) (designated an orphan drug by FDA for this use). Safety and efficacy not evaluated in patients with ≥25% involvement of bone marrow by lymphoma and/or impaired bone marrow reserve (e.g., prior myeloablative therapies, prior external beam radiation to >25% of active marrow, neutrophil count <1500/mm3).

Ibritumomab tiuxetan therapeutic regimen also used for consolidation treatment of newly diagnosed follicular NHL in patients who have achieved partial or complete response to first-line induction chemotherapy. Safety and efficacy not evaluated in patients with ≥25% involvement of bone marrow by lymphoma and/or impaired bone marrow reserve (e.g., prior myeloablative therapies, prior external beam radiation to >25% of active marrow, platelet count <150,000/mm3).