Tolterodine Tartrate and Zidovudine

• Generic Name: tolterodine
• Dosage Forms: n.a.
• Other Brand Names: Detrol, Detrol LA

Treatment of overactive bladder for the relief of symptoms associated with voiding such as urge urinary incontinence, urgency, and frequency. Efficacy not established in pediatric patients.

Tolterodine (conventional tablets) appears to be as effective as conventional oxybutynin in reducing urinary symptoms in patients with overactive bladder and is associated with a lower incidence of dry mouth.

Tolterodine (2 mg twice daily as conventional tablets) appears to be less effective than extended-release oxybutynin (10 mg once daily as extended-release tablets) in reducing urinary symptoms in patients with overactive bladder. The incidence of adverse effects (e.g., dry mouth) is similar between conventional tolterodine tartrate and extended-release oxybutynin.

Single daily doses of extended-release capsules of tolterodine tartrate appear to be slightly more effective in relieving certain urinary symptoms (i.e., urge incontinence) than 2 daily doses of conventional tablets of the drug.

• Generic Name: zidovudine
• Dosage Forms: n.a.
• Other Brand Names: Retrovir

Zidovudine (also known as AZT) is used together with other medicines for the treatment of human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS). Zidovudine is used to slow the progression of disease in patients infected with HIV who have advanced symptoms, early symptoms, or no symptoms at all. Zidovudine is also used to help prevent pregnant women who have HIV from passing the virus to their babies during pregnancy and at birth.

Zidovudine will not cure or prevent HIV infection or AIDS, however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of problems that usually result from AIDS or HIV disease. Zidovudine will not keep you from spreading HIV to other people. People who receive zidovudine may continue to have the problems usually related to AIDS or HIV disease.

Zidovudine is available only with your doctor's prescription.