Topotecan Hydrochloride and Trimipramine

• Generic Name: topotecan
• Dosage Forms: n.a.
• Other Brand Names: Hycamtin

Treatment of advanced ovarian cancer in patients with disease that has recurred or progressed following therapy with platinum-based (i.e., cisplatin, carboplatin) regimens.

Second-line therapy for treatment-sensitive small cell lung cancer (defined as disease initially responding to first-line chemotherapy with subsequent relapse no sooner than 60–90 days following completion of first-line therapy when topotecan is administered IV or at least 45 days following completion of first-line therapy when topotecan is administered orally).

Used in combination with cisplatin for the treatment of stage IV-B, recurrent, or persistent cervical cancer not amenable to curative treatment with surgery and/or radiation therapy.

• Generic Name: trimipramine
• Dosage Forms: n.a.
• Other Brand Names: Surmontil

Trimipramine is a tricyclic antidepressant. Trimipramine affects chemicals in the brain that may be unbalanced in people with depression.

Trimipramine is used to treat symptoms of depression.

Trimipramine may also be used for purposes not listed in this medication guide.