Tranylcypromine Sulfate and Zerit Pediatrics

• Generic Name: tranylcypromine
• Dosage Forms: n.a.
• Other Brand Names: Parnate

Treatment of major depressive disorder without melancholia.

Efficacy in major depressive disorder with melancholia (endogenous features) not established.

MAO inhibitors appear particularly effective in treatment of major depressive disorder with atypical features, although other antidepressants (e.g., SSRIs) may initially be used because of their more favorable adverse effect profile.

Because of potential for serious adverse effects and necessity of dietary restrictions, MAO inhibitors (e.g., phenelzine, tranylcypromine) generally are not used as initial therapy for major depressive disorder, but are reserved for carefully selected patients who can be closely supervised and who have depression refractory to other antidepressants (e.g., SSRIs, SNRIs, TCAs) or in whom other therapies are contraindicated.

• Generic Name: stavudine
• Dosage Forms: n.a.
• Other Brand Names: Zerit, Zerit XR

Stavudine is used in combination with other medicines in the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus responsible for acquired immune deficiency syndrome (AIDS). It is used to slow the progression of disease in patients infected with HIV who have advanced symptoms, early symptoms, or no symptoms at all.

Stavudine will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of problems usually related to AIDS or HIV disease.

Stavudine will not keep you from spreading HIV to other people. People who receive this medicine may continue to have other problems usually related to AIDS or HIV disease.

This medicine is available only with your doctor's prescription.