Trexall Oral and Vizimpro

• Generic Name: methotrexate
• Dosage Forms: tablet, film coated
• Other Brand Names: Rheumatrex Dose Pack, Trexall, Xatmep, Otrexup, Rasuvo, Methotrexate Sodium, Preservative Free

Methotrexate tablets are used alone or together with other medicines to treat several types of cancer such as breast, head and neck, lung, blood, bone, lymph node, uterus cancers, and severe rheumatoid arthritis. It is also used to control symptoms of severe psoriasis in adults who have not been helped by other treatments.

Methotrexate oral solution is used to treat acute lymphoblastic leukemia (ALL) in children, and help manage polyarticular juvenile idiopathic arthritis (pJIA) in children who had other treatments that did not work well.

Methotrexate belongs to the group of medicines known as antineoplastics (cancer medicines). It blocks an enzyme that is needed by cells to live. This interferes with the growth of cancer cells, which are eventually destroyed by the body. For patients with arthritis or psoriasis, methotrexate may work by improving the immune system.

This medicine is available only with your doctor's prescription.

• Generic Name: dacomitinib
• Dosage Forms: tablet, film coated
• Other Brand Names: Vizimpro

Vizimpro (dacomitinib) is a prescription medicine used to treat non-small cell lung cancer that has spread to other parts of the body (metastasised).

Vizimpro is given only if your tumor has a specific genetic marker (an abnormal "EGFR" gene).

It is not known if Vizimpro is safe and effective in children.