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Trezix and Trovan

Determining the interaction of Trezix and Trovan and the possibility of their joint administration.

Check result:
Trezix <> Trovan
Relevance: 22.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

A minor pharmacokinetic interaction between trovafloxacin and caffeine resulted in increases in the AUC and Cmax for caffeine. The mechanism is not known. The manufacturer does not consider these changes in caffeine exposure to be clinically significant.

References
  • "Product Information. Trovan (trovafloxacin)." Pfizer US Pharmaceuticals, New York, NY.
Trezix

Generic Name: acetaminophen / caffeine / dihydrocodeine

Brand name: Dvorah, Panlor Tablet, Trezix, Panlor DC, Panlor SS, Zerlor

Synonyms: n.a.

Trovan

Generic Name: trovafloxacin

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction