Trifluridine and Tipiracil Hydrochloride and Tuzistra XR

• Generic Name: tipiracil / trifluridine
• Dosage Forms: n.a.
• Other Brand Names: Lonsurf

Treatment of metastatic colorectal cancer previously treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-containing regimens; a vascular endothelial growth factor inhibitor (anti-VEGF therapy); and, in patients with tumors bearing wild-type (nonmutated) KRAS gene, an epidermal growth factor receptor inhibitor (anti-EGFR therapy).

• Generic Name: chlorpheniramine / codeine
• Dosage Forms: suspension, extended release
• Other Brand Names: Codar AR, Tuzistra XR, Codeprex, Cotab A, Cotab AX, Notuss-AC, Z-Tuss AC, Zodryl AC 25, Zodryl AC 30, Zodryl AC 35, Zodryl AC 50, Zodryl AC 40, Zodryl AC 60, Zodryl AC 80, EndaCof-C, TL-Hist CM, Zodryl AC Adult, Lexuss 210, EndaCof-C, Tuxarin ER

Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Codeine is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex.

Tuzistra XR is a combination medicine used to treat cough, runny nose, sneezing, itching, and watery eyes caused by allergies or the common cold. Tuzistra XR is for use in adults and children who are at least 12 years old.

Do not give this medicine to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Tuzistra XR may also be used for purposes not listed in this medication guide.