Trifluridine and Tipiracil Hydrochloride and Zaroxolyn

• Generic Name: tipiracil / trifluridine
• Dosage Forms: n.a.
• Other Brand Names: Lonsurf

Treatment of metastatic colorectal cancer previously treated with fluoropyrimidine-, oxaliplatin-, and irinotecan-containing regimens; a vascular endothelial growth factor inhibitor (anti-VEGF therapy); and, in patients with tumors bearing wild-type (nonmutated) KRAS gene, an epidermal growth factor receptor inhibitor (anti-EGFR therapy).

• Generic Name: metolazone
• Dosage Forms: tablet
• Other Brand Names: Zaroxolyn, Mykrox

Zaroxolyn is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Zaroxolyn is used to treat fluid retention (edema) in people with congestive heart failure, or a kidney disorder such as nephrotic syndrome. This medicine is also used to treat high blood pressure (hypertension).

Zaroxolyn may also be used for purposes not listed in this medication guide.