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Trinipatch 0.2 and Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)

Determining the interaction of Trinipatch 0.2 and Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets) and the possibility of their joint administration.

Check result:
Trinipatch 0.2 <> Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)
Relevance: 26.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Omeprazole may inhibit the drug delivery of oral nitrates. Antianginal effects may be diminished, and myocardial ischemia may be exacerbated. If an interaction is suspected, alternate acid-suppressant therapy may be considered.

References
  • Kajinami K, Mabuchi H "Omeprazole and diminished antianginal drug delivery." Ann Intern Med 121 (1994): 385-6
Trinipatch 0.2

Generic Name: nitroglycerin

Brand name: Gonitro, Nitrolingual, NitroMist, Nitrostat, Nitro-Time, Gonitro, Minitran, Nitro TD Patch-A, Nitro-Dur, Nitro-Bid, Nitrol Appli-Kit, Rectiv

Synonyms: Nitroglycerin (oral/sublingual), Nitroglycerin

Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)

Generic Name: omeprazole / sodium bicarbonate

Brand name: Zegerid, Zegerid OTC

Synonyms: Zegerid

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.