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Tubersol and Zostavax

Determining the interaction of Tubersol and Zostavax and the possibility of their joint administration.

Check result:
Tubersol <> Zostavax
Relevance: 20.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Zoster vaccine live may interfere with the response to tuberculin purified protein derivative and lead to false-negative test results. Tuberculin purified protein derivative may be given before or at the same time as zoster vaccine live. However, a person who has been vaccinated with zoster vaccine live may need to wait four to six weeks before getting tested with tuberculin purified protein derivative. It is important to tell the doctor about all other medications being used, including vitamins and herbs. Do not stop using any medications without first talking to the doctor.

Professional:

ADJUST DOSING INTERVAL: Reactivity to diagnostic skin test antigens may be temporarily depressed in patients who have recently been vaccinated with live virus vaccines. Falsely insignificant or false-negative results may occur in such patients.

MANAGEMENT: Clinicians should be aware of the potential for falsely insignificant or false-negative results when performing delayed-hypersensitivity skin testing on patients who have recently received live virus vaccines. Diagnostic skin test antigens should be administered before, simultaneously with, or 4 to 6 weeks after immunization.

References
  • "Product Information. MSTA Mumps Skin Test Antigen (mumps skin test antigen)." Aventis Pharmaceuticals, Swiftwater, PA.
  • "Product Information. Multitest CMI (skin test antigens, multiple)." Aventis Pharmaceuticals, Swiftwater, PA.
  • "Product Information. Tuberculin PPD (Mantoux) (tuberculin purified protein derivative)." Connaught Laboratories Ltd, Toronto, ON.
Tubersol

Generic Name: tuberculin purified protein derivative

Brand name: Aplisol, Tubersol

Synonyms: n.a.

Zostavax

Generic Name: zoster vaccine live

Brand name: Zostavax

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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Disease interaction