Tylenol Cold Severe Congestion and Zantac (Ranitidine Syrup)
Determining the interaction of Tylenol Cold Severe Congestion and Zantac (Ranitidine Syrup) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that ranitidine may potentiate the hepatotoxicity of acetaminophen, however, a double-blind placebo-controlled crossover study has failed to confirm this finding in humans. Acetaminophen dosage adjustments are not indicated.
- Rogers SA, Gale KC, Newton JF, et al "Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity." J Pharmacol Exp Ther 245 (1988): 887-94
- Jack D, Thomas M, Skidmore IF "Ranitidine and paracetamol metabolism." Lancet 2 (1985): 1067
Generic Name: acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine
Brand name: Duraflu, Tylenol Cold Severe Congestion, Robitussin Cold Cough and Flu, Theraflu Max-D Severe Cold & Flu, Sudafed Cold and Cough Liquicaps, Theraflu Chest and Cough, Tylenol Cold Severe Congestion Non-Drowsy, Sudafed Sinus and Cold Liquicaps, Phlemgesic, Maxiflu DM, Flutabs
Synonyms: n.a.
Generic Name: ranitidine
Brand name: Zantac
Synonyms: Zantac
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Tylenol Cold Severe Congestion-Zantac (Ranitidine Tablets and Capsules)
- Tylenol Cold Severe Congestion-Zantac Cool Mint
- Tylenol Cold Severe Congestion-Zantac Injection
- Tylenol Cold Severe Congestion-Zapzyt Cleansing Topical
- Tylenol Cold Severe Congestion-Zapzyt Topical
- Tylenol Cold Severe Congestion-Zarah
- Zantac (Ranitidine Syrup)-Tylenol Cough/Sore Throat (Acetaminophen and Dextromethorphan Liquid)
- Zantac (Ranitidine Syrup)-Tylenol Cough/Sore Throat (Acetaminophen, Dextromethorphan, and Doxylamine Liquid)
- Zantac (Ranitidine Syrup)-Tylenol Infants
- Zantac (Ranitidine Syrup)-Tylenol Junior
- Zantac (Ranitidine Syrup)-Tylenol Maximum Strength Flu Nighttime
- Zantac (Ranitidine Syrup)-Tylenol NightTime Cold & Flu