Venclexta and Welchol (Colesevelam Oral Suspension)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Colesevelam may decrease the blood levels and effects of venetoclax. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Coadministration of bile acid sequestrants may reduce the absorption of venetoclax, possibly reducing its pharmacologic effect. Bile acid sequestrants can bind certain drugs in the intestine to form an insoluble complex that is excreted in the feces.

MANAGEMENT: If concomitant use is required, venetoclax should be administered at least 4 to 6 hours after the bile acid sequestrant. Close clinical and laboratory monitoring may be considered during coadministration, since adjusting the dosing interval may not completely prevent the interaction.

Venclexta

Generic Name: venetoclax

Brand name: Venclexta, Venclexta Starting Pack

Synonyms: n.a.

What is Venclexta?

Welchol (Colesevelam Oral Suspension)

Generic Name: colesevelam

Brand name: Welchol, Colesevelam Hydrochloride

Synonyms: Welchol

What is Welchol (Colesevelam Oral Suspension)?