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Verteporfin Intravenous, Injection and Vibramycin Hyclate

Determining the interaction of Verteporfin Intravenous, Injection and Vibramycin Hyclate and the possibility of their joint administration.

Check result:
Verteporfin Intravenous, Injection <> Vibramycin Hyclate
Relevance: 16.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using doxycycline together with verteporfin may cause an increase in photosensitivity reactions, which could cause your skin to burn. You should be advised to avoid exposure to sunlight or bright indoor light for 5 days after administration of verteporfin. Contact your doctor if your condition worsens. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Concomitant use of verteporfin with other known photosensitizing agents may increase the risk of photosensitivity reactions. Medicinal products with known phototoxic or photoallergic potential include fluoroquinolones, phenothiazines, retinoids, sulfonamides, sulfonylureas, tetracyclines, thiazide diuretics, griseofulvin, and hypericin extracts (e.g., St John's Wort).

MANAGEMENT: Caution is advised and pharmacologic response to photodynamic therapy should be carefully monitored if concomitant use of other photosensitizing agents cannot be avoided. Patients should be advised to avoid exposure of skin or eyes to sunlight or bright indoor lights (e.g., examination lamps, operating room lamps, tanning beds, lights at close proximity) for 5 days after administration of verteporfin.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Multum Information Services, Inc. Expert Review Panel"
  • "Product Information. Visudyne (verteporfin)" Valeant Pharmaceuticals, Costa Mesa, CA.
Verteporfin Intravenous, Injection

Generic Name: verteporfin

Brand name: Visudyne

Synonyms: Verteporfin

Vibramycin Hyclate

Generic Name: doxycycline

Brand name: Acticlate, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Mondoxyne NL, Monodox, Morgidox, Oracea, Oraxyl, Periostat Targadox, Vibramycin Calcium, Vibramycin Hyclate, Vibramycin monohydrate, Vibra-Tabs, Adox Pak 2/100, Adoxa, Adoxa Pak 1/100, Adoxa Pak 1/150, Avidoxy, TargaDOX, Vibramycin, Doxy 100, TargaDOX

Synonyms: Doxycycline

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.