Yohimbine and Zyvox

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using linezolid together with yohimbine. Using these medications together can increase the blood levels or add to the side effects of linezolid, which can lead to increased blood pressure. You should 14 days after you stop using an MAOI before you start using yohimbine. You may need a dose adjustment or need your blood pressure checked more often if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Theoretically, yohimbine may precipitate severe hypertensive reactions and hyperpyrexia in patients treated with monoamine oxidase inhibitors (MAOIs). Yohimbine has been shown to induce the release of norepinephrine in patients with essential hypertension. This action could produce a synergistic sympathomimetic effect with MAOIs, which enhance norepinephrine storage in adrenergic neurons.

MANAGEMENT: While clinical data are lacking, yohimbine should preferably not be used with MAOIs or other agents that possess MAOI activity (e.g., furazolidone, linezolid, procarbazine). At least 14 days should elapse between discontinuation of MAOI therapy and initiation of treatment with yohimbine.

Yohimbine

Generic Name: yohimbine

Brand name:

Synonyms: Yohimbine (Oral)

What is Yohimbine?

Zyvox

Generic Name: linezolid

Brand name: Zyvox

Synonyms: n.a.

What is Zyvox?