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Alcohol in Dextrose and Procainamide injection

Determining the interaction of Alcohol in Dextrose and Procainamide injection and the possibility of their joint administration.

Check result:
Alcohol in Dextrose <> Procainamide injection
Relevance: 16.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Ethanol may increase the acetylation of procainamide. Subtherapeutic plasma levels of procainamide may result in some patients. Because the acetylated metabolite of procainamide also possesses antiarrhythmic properties, the clinical effects are unclear.

References
  • Olsen H, Morland J "Ethanol-induced increase in procainamide acetylation in man." Br J Clin Pharmacol 13 (1982): 203-8
Alcohol in Dextrose

Generic Name: ethanol

Brand name: Ablysinol

Synonyms: Alcohol, Dehydrated Alcohol Injection

Procainamide injection

Generic Name: procainamide

Brand name: Pronestyl, Procan SR, Pronestyl-SR, Procanbid

Synonyms: Procainamide (injection), Procainamide

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle