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Carafate (Sucralfate Oral Suspension) and Quinidex Extentabs

Determining the interaction of Carafate (Sucralfate Oral Suspension) and Quinidex Extentabs and the possibility of their joint administration.

Check result:
Carafate (Sucralfate Oral Suspension) <> Quinidex Extentabs
Relevance: 10.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Limited clinical data suggest that sucralfate may decrease the gastrointestinal absorption of quinidine. Serum quinidine levels and quinidine effect may be decreased. The mechanism is not known. Close observation for clinical and laboratory evidence of altered quinidine effect is recommended if these drugs must be used together. Patients should be advised to take quinidine at least 2 hours before or 6 hours after sucralfate to minimize a potential interaction.

References
  • Rey AM, Gums JG "Altered absorption if digoxin, sustained-release quinidine, and warfarin with sucralfate administration." Ann Pharmacother 25 (1991): 745-6
Carafate (Sucralfate Oral Suspension)

Generic Name: sucralfate

Brand name: Carafate

Synonyms: Carafate

Quinidex Extentabs

Generic Name: quinidine

Brand name: Quin-G, Cardioquin, Quinora, Quinidex Extentabs, Quinaglute Dura-Tabs, Quin-Release

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.