Cisapride Suspension and Diazepam Oral Solution Concentrate
Determining the interaction of Cisapride Suspension and Diazepam Oral Solution Concentrate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Cisapride is no longer on the market in the US. Do not take cisapride with any other medication.
Professional:MONITOR: Cisapride may increase the rate but not the extent of diazepam absorption. In one study, coadministration of cisapride significantly increased impairment of reaction time in the first 45 minutes after diazepam administration.
MANAGEMENT: It is recommended that patients be monitored for excessive CNS depression during concomitant therapy. Patients should be advised to report prolonged or excessive sedation to their physician.
- Greiff JMC, Rowbotham D "Pharmacokinetic drug interactions with gastrointestinal motility modifying agents." Clin Pharmacokinet 27 (1994): 447-61
Generic Name: cisapride
Brand name: Propulsid
Synonyms: Cisapride Tablets
Generic Name: diazepam
Brand name: Valium, Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Zetran
Synonyms: Diazepam
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cisapride Suspension-Diazepam rectal
- Cisapride Suspension-Diazepam Rectal Gel
- Cisapride Suspension-Diazepam Solution
- Cisapride Suspension-Diazepam Tablet
- Cisapride Suspension-Diazepam Tablets
- Cisapride Suspension-Diazoxide
- Diazepam Oral Solution Concentrate-Cisapride Tablets
- Diazepam Oral Solution Concentrate-Cisatracurium
- Diazepam Oral Solution Concentrate-Cisatracurium Besylate
- Diazepam Oral Solution Concentrate-Cisatracurium Besylate Injection
- Diazepam Oral Solution Concentrate-Cisatracurium besylate Intravenous
- Diazepam Oral Solution Concentrate-Cisplatin