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Cisapride Tablets and Diazepam Intensol

Determining the interaction of Cisapride Tablets and Diazepam Intensol and the possibility of their joint administration.

Check result:

Cisapride Tablets <> Diazepam Intensol

Relevance: 25.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Cisapride is no longer on the market in the US. Do not take cisapride with any other medication.

Professional:

MONITOR: Cisapride may increase the rate but not the extent of diazepam absorption. In one study, coadministration of cisapride significantly increased impairment of reaction time in the first 45 minutes after diazepam administration.

MANAGEMENT: It is recommended that patients be monitored for excessive CNS depression during concomitant therapy. Patients should be advised to report prolonged or excessive sedation to their physician.

References

Greiff JMC, Rowbotham D "Pharmacokinetic drug interactions with gastrointestinal motility modifying agents." Clin Pharmacokinet 27 (1994): 447-61

Cisapride Tablets

Generic Name: cisapride

Brand name: Propulsid

Synonyms: n.a.

What is Cisapride Tablets?

Diazepam Intensol

Generic Name: diazepam

Brand name: Diazepam Intensol, Diastat, Diastat AcuDial, Diastat Pediatric, Valium, Zetran

Synonyms: n.a.

What is Diazepam Intensol?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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