Cleocin Phosphate IV and Gengraf (Cyclosporine Capsules, Modified)
Determining the interaction of Cleocin Phosphate IV and Gengraf (Cyclosporine Capsules, Modified) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using clindamycin together with cycloSPORINE may decrease the effects of cycloSPORINE. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Cyclosporine plasma concentrations may be reduced during coadministration with oral clindamycin. The mechanism is unknown.
MANAGEMENT: Cyclosporine levels should be monitored when clindamycin is initiated or discontinued in a patient previously stabilized on cyclosporine. Transplant patients should be observed for signs of rejection during concomitant therapy and for cyclosporine toxicity after discontinuation of clindamycin.
- Thurnheer R, Laube I, Speich R "Possible interaction between clindamycin and cyclosporin." Br Med J 319 (1999): 163
Generic Name: clindamycin
Brand name: Cleocin, Cleocin Pediatric, Cleocin HCl, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage, Clindesse, ClindaMax Vaginal
Synonyms: Cleocin Phosphate
Generic Name: cyclosporine
Brand name: Gengraf, Neoral, Sandimmune, Sandimmune
Synonyms: Gengraf (Capsules, Modified), Gengraf
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cleocin Phosphate IV-Gengraf (Cyclosporine Oral Solution, Modified)
- Cleocin Phosphate IV-Gengraf Capsules
- Cleocin Phosphate IV-Gengraf Oral
- Cleocin Phosphate IV-Gengraf Oral Solution
- Cleocin Phosphate IV-Genicin
- Cleocin Phosphate IV-Genicin Vita-Q
- Gengraf (Cyclosporine Capsules, Modified)-Cleocin T
- Gengraf (Cyclosporine Capsules, Modified)-Cleocin T (Clindamycin Gel and Lotion)
- Gengraf (Cyclosporine Capsules, Modified)-Cleocin T (Clindamycin Solution and Swab)
- Gengraf (Cyclosporine Capsules, Modified)-Cleocin T Topical
- Gengraf (Cyclosporine Capsules, Modified)-Cleocin Topical Solution
- Gengraf (Cyclosporine Capsules, Modified)-Cleocin Vaginal