Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Fumarate and Ziana

• Generic Name: cobicistat / darunavir / emtricitabine / tenofovir alafenamide
• Dosage Forms: n.a.
• Other Brand Names: Symtuza

Darunavir, cobicistat, emtricitabine, and tenofovir alafenamide fumarate is a four-drug combination of darunavir (DRV), an HIV-1 protease inhibitor, cobicistat (COBI), a CYP3A inhibitor, and emtricitabine (FTC) and tenofovir alafenamide (TAF), both HIV-1 NRTIs, and is indicated as a complete regimen for the treatment of HIV-1 infection in adults who have no prior antiretroviral treatment history or who are virologically suppressed (HIV-1 RNA less than 50 copies per mL) on a stable antiretroviral regimen for at least 6 months and have no known substitutions associated with resistance to darunavir or tenofovir.

• Generic Name: clindamycin / tretinoin topical
• Dosage Forms: gel
• Other Brand Names: Veltin, Ziana

Ziana is a gel containing a combination of clindamycin and tretinoin. Clindamycin is an antibiotic. It fights bacteria in the body.

Tretinoin is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.

Ziana is used to treat severe nodular acne in adults and children who are at least 12 years old.

Ziana may also be used for purposes other than those listed in this medication guide.