Desipramine Hydrochloride and Meclofenamate

• Generic Name: desipramine
• Dosage Forms: n.a.
• Other Brand Names: Norpramin

Management of major depressive disorder.

Results of several studies of TCAs in preadolescent and adolescent patients with major depression indicate lack of overall efficacy in this age group.

Has been used for the management of panic disorder with or without agoraphobia.

Has been used for the management of eating disorders (e.g., bulimia, anorexia nervosa) with equivocal results; avoid use in underweight individuals and in those exhibiting suicidal ideation.

Has been used for the short-term management of acute depressive episodes in bipolar disorder.

TCAs associated with a greater risk of precipitating hypomania or manic episodes than other classes of antidepressants; should always be used in combination with a mood stabilizer (e.g., lithium).

Has been used for the management of acute depressive episodes (in combination with an antipsychotic) in patients with schizophrenia.

Among the drugs of choice for the symptomatic treatment of postherpetic neuralgia.

Less effective for insomnia and associated with more serious adverse reactions than conventional hypnotics.

Not recommended for use in children with ADHD. (See Pediatric Use under Cautions.)

• Generic Name: meclofenamate
• Dosage Forms: n.a.
• Other Brand Names:

  Meclomen

Meclofenamate is a nonsteroidal anti-inflammatory drug (NSAID). Meclofenamate works by reducing hormones that cause inflammation and pain in the body.

Meclofenamate is used to treat fever or mild to moderate pain in adults. Meclofenamate is also used to relieve symptoms of osteoarthritis or rheumatoid arthritis in adults, and juvenile arthritis in children who are at least 14 years old.

Meclofenamate is also used to treat menstrual pain or heavy menstrual bleeding.

Meclofenamate is sometimes used long-term to treat symptoms of ankylosing spondylitis, gouty arthritis, or shoulder pain caused by bursitis or tendinitis.

Meclofenamate may also be used for purposes not listed in this medication guide.