Dextrose and Eliglustat Tartrate

• Generic Name: glucose
• Dosage Forms: n.a.
• Other Brand Names: Dextrose, BD Glucose, Dex4, Insta-Glucose, Relion Grape, TRUEplus, Trutol Fruit Punch, Rematex, Ziks Arthritis Pain Relief

Dextrose (glucose) is a form of natural sugar that is normally produced by the liver. Glucose is a source of energy, and all the cells and organs in your body need glucose to function properly. Glucose as a medication is given either by mouth (orally) or by injection.

Dextrose is used to treat very low blood sugar (hypoglycemia), most often in people with diabetes mellitus. Dextrose is given by injection to treat insulin shock (low blood sugar caused by using insulin and then not eating a meal or eating enough food afterward). This medicine works by quickly increasing the amount of glucose in your blood.

Dextrose is also used to provide carbohydrate calories to a person who cannot eat because of illness, trauma, or other medical condition. It is sometimes given to people who are sick from drinking too much alcohol.

Dextrose may also be used to treat hyperkalemia (high levels of potassium in your blood).

• Generic Name: eliglustat
• Dosage Forms: n.a.
• Other Brand Names: Cerdelga

Long-term treatment of nonneuronopathic (type 1) Gaucher disease in patients who are extensive, intermediate, or poor metabolizers of CYP2D6.

Patient selection and dosing based on CYP2D6 metabolizer status; determine patient's CYP2D6 genotype with an FDA-cleared test prior to initiating therapy.

Ultrarapid CYP2D6 metabolizers may not achieve adequate plasma concentrations to achieve a therapeutic effect. A specific dosage cannot be recommended for patients whose CYP2D6 genotype cannot be determined (indeterminate metabolizers).

Designated an orphan drug by FDA for treatment of type 1 Gaucher disease.