Goserelin Acetate and Kalexate

• Generic Name: goserelin
• Dosage Forms: n.a.
• Other Brand Names: Zoladex

Palliative treatment of advanced prostate cancer. Considered one of several first-line options for hormonal therapy; other options include orchiectomy, estrogens, and antiandrogens.

In clinical studies, goserelin (3.6 mg every 4 weeks) was as effective as orchiectomy. Clinical outcome in patients receiving goserelin 10.8 mg every 12 weeks expected to be similar to that of patients receiving goserelin 3.6 mg every 4 weeks.

Also used as an adjunct to radiation therapy in patients with stage III[C]) prostate cancer.

Treatment of locally confined stage T2b-T4 (B2-C) prostate cancer in conjunction with flutamide and radiation therapy.

Palliative treatment of endometriosis. Experience with goserelin has been limited to women ≥18 years of age who received consecutive therapy (3.6 mg every 4 weeks) for 6 months.

Palliative treatment of advanced breast cancer in premenopausal and perimenopausal women.

Used as an endometrial-thinning agent prior to endometrial ablation procedures for the treatment of dysfunctional uterine bleeding.

• Generic Name: sodium polystyrene sulfonate
• Dosage Forms: oral, rectal powder
• Other Brand Names: Kalexate, Kayexalate, Kionex

Kalexate binds itself to potassium in your digestive tract. This helps prevent your body from absorbing too much potassium.

Kalexate is used to treat high levels of potassium in the blood, also called hyperkalemia.

Kalexate works differently from other medicines because it passes into your intestines without being absorbed into your blood stream.

Kalexate may also be used for purposes not listed in this medication guide.