Hyaluronidase and trastuzumab and Paclitaxel Concentrate Injection
Determining the interaction of Hyaluronidase and trastuzumab and Paclitaxel Concentrate Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using trastuzumab together with PACLitaxel may increase the effects of trastuzumab. Contact your doctor if you experience chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling, swelling, rapid weight gain, cough or wheezing, white patches or sores inside your mouth or on your lips, or fever, chills, body aches, and flu symptoms. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Non-human studies have demonstrated that paclitaxel can significantly increase the serum levels and decrease the clearance of trastuzumab. The mechanism is unknown.
MANAGEMENT: Patients should be monitored closely for signs of trastuzumab toxicity (e.g., cardiotoxicity, bone marrow depression).
- "Product Information. Herceptin (trastuzumab)." Genentech, South San Francisco, CA.
Generic Name: hyaluronidase / trastuzumab
Brand name: Herceptin Hylecta
Synonyms: Trastuzumab and Hyaluronidase
Generic Name: paclitaxel
Brand name: Onxol, Taxol
Synonyms: Paclitaxel, PACLitaxel (Conventional)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Hyaluronidase and trastuzumab-Paclitaxel Intravenous
- Hyaluronidase and trastuzumab-Paclitaxel Novaplus
- Hyaluronidase and trastuzumab-Paclitaxel protein-bound
- Hyaluronidase and trastuzumab-Paclitaxel protein-bound Intravenous
- Hyaluronidase and trastuzumab-Pacnex
- Hyaluronidase and trastuzumab-Pacnex LP
- Paclitaxel Concentrate Injection-Hyaluronidase injection
- Paclitaxel Concentrate Injection-Hyaluronidase Injection (Human)
- Paclitaxel Concentrate Injection-Hyaluronidase Subcutaneous, Injection
- Paclitaxel Concentrate Injection-Hyate:C
- Paclitaxel Concentrate Injection-Hybrisil
- Paclitaxel Concentrate Injection-Hycamtin