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Lorazepam Intensol and Pemoline

Determining the interaction of Lorazepam Intensol and Pemoline and the possibility of their joint administration.

Check result:
Lorazepam Intensol <> Pemoline
Relevance: 06.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Pemoline may increase the risk of seizures and decrease the effectiveness of LORazepam. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience a loss of seizure control or your condition changes during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Decreased seizure threshold has been reported in patients receiving pemoline concomitantly with antiepileptic medications. The mechanism of this interaction has not been reported.

MANAGEMENT: These drugs should be coadministered cautiously with careful clinical monitoring. Patients should be advised to notify their physician if they experience loss of seizure control.

References
  • "Product Information. Cylert (pemoline)." Abbott Pharmaceutical, Abbott Park, IL.
Lorazepam Intensol

Generic Name: lorazepam

Brand name: Ativan, Lorazepam Intensol

Synonyms: Lorazepam Intensol (Oral)

Pemoline

Generic Name: pemoline

Brand name:

Synonyms: Pemoline (Oral)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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