Maraviroc Oral Solution and Tipranavir Capsules
Determining the interaction of Maraviroc Oral Solution and Tipranavir Capsules and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with tipranavir/ritonavir does not appear to significantly alter the plasma concentrations of maraviroc. In 12 study subjects, coadministration of maraviroc (150 mg twice a day) with tipranavir/ritonavir (500 mg/200 mg twice a day) reduced the peak plasma concentration (Cmax) of maraviroc by 14% and increased the trough plasma concentration (Cmin) by 80%, but had no effect on the overall systemic exposure. No dosage adjustment of maraviroc is necessary when coadministered with tipranavir/ritonavir in the absence of concomitant potent CYP450 3A4 inhibitors such as itraconazole, ketoconazole, delavirdine, clarithromycin, telithromycin, or nefazodone.
- "Product Information. Selzentry (maraviroc)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
Generic Name: maraviroc
Brand name: Selzentry
Synonyms: Maraviroc
Generic Name: tipranavir
Brand name: Aptivus
Synonyms: Tipranavir
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Maraviroc Oral Solution-Tipranavir Oral Solution
- Maraviroc Oral Solution-Tirofiban
- Maraviroc Oral Solution-Tirofiban Intravenous
- Maraviroc Oral Solution-Tirosint
- Maraviroc Oral Solution-Tirosint-Sol
- Maraviroc Oral Solution-Tisagenlecleucel
- Tipranavir Capsules-Maraviroc Tablets
- Tipranavir Capsules-Marcaine
- Tipranavir Capsules-Marcaine HCl
- Tipranavir Capsules-Marcaine Preservative Free
- Tipranavir Capsules-Marcaine Spinal
- Tipranavir Capsules-Marcaine/Epinephrine